医院感染常见病原菌耐药性分析

材料写作网    时间: 2020-08-07 04:33:22     阅读:次

【摘要】 目的了解医院常见病原菌分布及耐药状况。方法 2009年1~5月期间,我院临床感染性标本中病原菌的分布及耐药率进行回顾性分析。结果 所分离的病原菌对抗菌药物均产生了较严重的耐药性,耐药率高的抗菌药物有:头孢曲松钠(941%),环丙沙星(918%),苯唑青霉素(870%),头孢他啶、头孢吡肟、氨曲南、复方新诺明、红霉素、(均>500%)。敏感率较高的抗菌药物为:万古霉素(I 19%)、利奈唑胺(30%)、亚胺培南(40%)。结论 为防止医院感染,减少ESBLs菌株的产生,控制耐药菌株的播散和流行,临床需严格控制第三代头孢菌素及其他广谱β内酰胺类抗菌药物的使用,做到合理应用抗菌药物。

【关键词】

病原菌;耐药性;分析

Analysis of Drug Resistance of Common Nosocomial Infection Pathogens

LIU Wei,LENG Yingrong,LUO Guangying,et al.

Affiliated hospital of Guiyang medical college,guizhou 550004,China

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【Abstract】 Objective To know the etiology and drug resistance of common nosocomial infection pathogens Methods The hospital carried out retrospective analysis on etiology and drug resistance of pathogens in clinical infectious sample from January to May 2009 ResultsPathogens separated have all produced serious drug resistance to antibacterial agents Agents with relatively higher drug resistance rate include: ceftriaxone sodium(941%), ciprofloxacin(918%), oxacillin(870%), ceftazidime, cefepime, aztreonam,SMZTMP and erythrocin (all>50%) Agents with relatively higher susceptibility rate inculde: vancomycin (119%), linezolid (30%) and imipenem (40%)Conclusion In order to prevent nosocomial infection, reduce ESBLs bacterial strain and take effective measures to contorl the prevalence of bacterial strain with drugresistance, thirdgeneration cephalosporins and other extendedspectrum βlactamases (ESBLs) shall be used in clinical application in strict control realize more rationally use of antimicrobi...

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