中药物质基础研究是中药继承、发展、创新的关键科学问题
[摘要]中医防病治病的用药形式为中药复方。单味中药（多为饮片）是处方药，是中药复方的组成元素。由于某味中药在不同复方中的'君、臣、佐、使“地位不同，研究中药的药效物质基础应以中药复方的化学成分为切入点，单味中药应该是全成分分析，质量稳定可控。中药物质基础研究是中药继承、发展、创新的关键科学问题。
[关键词]中药复方;药效物质基础;关键科学问题
Substance basis research on Chinese materia medica is one of key scientific
problems of inheriting， development and innovation of Chinese materia medica
YANG Xiu-wei
（School of Pharmaceutical Sciences， Peking University， Beijing 100191， China）
[Abstract]The compound Chinese materia medica is the medication pattern of the traditional Chinese medicine for the disease prevention and treatment. The single Chinese materia medica （mostly in decoction pieces） is the prescription composition of the compound Chinese materia medica. The study of the effective substance basis of Chinese materia medica should be based on the chemical compositions of the compound Chinese materia medica as an entry point considering the different status of ″Monarch， Minister， Assistant， and Guide″ for a certain single Chinese materia medica in the different compound Chinese materia medica while substance basis research of a certain single Chinese materia medica should be a full component analysis as well as both stable and controllable quality. Substance basis research on Chinese materia medica is one of key scientific problems of inheriting， development and innovation of Chinese materia medica.
[Key words]compound Chinese materia medica; effective substance basis; key scientific problem
doi：10.4268/cjcmm20151719
中药是以人种药理学（ethnopharmacology）为基础而发展起来的，在现代意义上的筛选开始之前就已经进行了为各种...
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