D—二聚体检测联合PTP评分对VTE的诊断价值评估
打开文本图片集
【摘要】 目的:评价D-Dimer PLUS测定血浆D-二聚体水平联合临床可能性预测量表(Pretest Probability,PTP)评分对静脉血栓栓塞症(Venous Thromboembolism,VTE)的诊断价值。方法:对2005年1月-2008年12月于中山大学附属第一医院就诊疑似诊断VTE的346例患者进行D-二聚体检测及PTP评分,并以影像学检查作为临床确诊手段。结果:应用ROC曲线分析单用血浆D-二聚体水平来诊断VTE时,最佳诊断点为95 μg/L,相应敏感性、特异性及阴性预测值分别为100%、26.25%及100%。以厂家推荐的130 μg/L为诊断点时,相应的阴性预测值仅有81.48%。D-Dimer检测结合PTP评分来诊断VTE时,以130 μg/L为诊断点时的阴性预测值达到了100%。与以95 μg/L为诊断点比较,使更多的人避免了不必要的影像学检查,减少了医疗资源的浪费;单用D-Dimer PLUS检测有漏诊情况,而结合PTP评分则无漏诊。结论:D-Dimer PLUS结合PTP评分对VTE的初筛有较高的诊断价值,对临床快速诊断VTE有较高的应用价值。
【关键词】 静脉血栓栓塞症; D-二聚体; 可能性预测量表
Value Estimation of Plasma D-Dimer Concentration Combination with PTP Scores on Diagnosing VTE/YE Zhuang-jian,LI Jun-xun,NIU Shi-qiong,et al.//Medical Innovation of China,2017,14(27):126-130
【Abstract】 Objective:To estimate the value of plasma D-Dimer concentration using D-Dimer PLUS combination with PTP scores on diagnosing VTE.Method:A total of 346 suspected VTE patients in the First Affiliated Hospital,Sun Yat-sen University from January 2005 to December 2008 were tested their plasma D-Dimer concentration using D-Dimer PLUS combination with PTP scores,at the same time,radiological diagnostic techniques are used as the final diagnosing methods.Result:When D-Dimer assay used as stand-alone test,95 μg/L was considered as the optimal cutoff value to diagnose VTE,having a sensitivity,speci...
== 试读已结束,如需继续阅读敬请充值会员 ==
|
本站文章均为原创投稿,仅供下载参考,付费用户可查看完整且有格式内容!
(费用标准:38元/2月,98元/2年,微信支付秒开通!) |
升级为会员即可查阅全文 。如需要查阅全文,请 免费注册 或 登录会员 |