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慢性阻塞性肺疾病的常见致病菌及耐药性分析

材料写作网    时间: 2020-08-01 04:22:06     阅读:次     手机站

【摘要】 目的:研究慢性阻塞性肺疾病(COPD)患者常见致病菌菌群分布及耐药性分析,以指导临床合理药。方法:收集本院2016年1-12月收住入院的404例COPD患者的痰标本进行细菌培养和耐药性分析。结果:在404例COPD患者中,分离出284株致病菌,其中革兰阴性杆菌占73.2%,以肺炎克雷伯氏菌(40.4%)、铜绿假单胞菌(23.1%)、大肠埃希氏菌(22.6%)占前3位;革兰阳性球菌占19.7%,以金黄色葡萄球菌(69.6%)、肺炎链球菌(21.4%)、粪肠球菌为(8.9%)多见;真菌占7.0%,以白色念珠菌(60.0%)、热带念珠菌(25.0%)为主。结论:COPD患者的致病菌组成不同,以革兰阴性杆菌为主,革兰阳性球菌感染比重有所上升。目前细菌耐药情况严峻,临床医生应根据患者的细菌药敏情况进行综合评估,制定合理的抗生素使用方案。

【关键词】 慢性阻塞性肺疾病; 致病菌; 耐药性

Analysis of the Common Pathogenic Bacteria and Drug Resistance in Chronic Obstructive Pulmonary Diseases/XIA Hui,LIU Shou-ming,XIA Qing-hua.//Medical Innovation of China,2017,14(24):103-105

【Abstract】 Objective:To study the distribution and drug resistance of common pathogenic bacteria in chronic obstructive pulmonary disease(COPD),so as to guide rational drug use in clinic.Method:Sputum samples of 404 patients with COPD in our hospital from January 2016 to December 2016 were collected for bacterial culture and drug resistance analysis.Result:284 pathogenic bacteria were separated from 404 COPD patients.Therein,Gram negative bacilli occupy 73.2%,among which Klebsiella Pneumoniae(40.4%),Pseudomonas Aeruginosa (23.1%) and Escherichia Coli(22.6%) rank top 3;Gram positive coccus occupy 19.7%,among which Staphylococcus Aureus(69.6%),Streptococcus Pneumoniae (21.4%) and Enterococcus Faecalis (8.9%) were common;fungus occupies 7.0%,which mainly includes Candida Albicans (60.0%) and Candida Tropicalis(25.0%).Conclusion:The constitution of COPD patients’ pathogenic bacteria is different,and...



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