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HCY、HS—CRP和LPa的检测在冠心病诊治中的临床意义的探讨

材料写作网    时间: 2021-02-24 04:14:01     阅读:

摘要:目的 同型半胱氨酸(HCY)、血清超敏C-反应蛋白(HS-CRP)、脂蛋白a[LP(a)]的联合检测对冠心病患者诊治中的临床意义。方法 收集我院2013年5月~2014年10月不同类型的冠心病患者126例:稳定性心绞痛(SAP)42 例、不稳定性心绞痛(UAP) 36 例、急性心肌梗死(AMI) 48 例,并随机抽取体检合格的健康人88例设为对照组,分别检测血清HCY、HS-CRP、LP(a)的水平。结果 冠心病组HCY、HS-CRP、LP(a)含量均明显高于对照组(P<0.05),对照组上述各项指标均在正常范围内。AMI组三项联合检测的阳性率和单独检测的阳性率随病程延长均逐渐提高。结论 在冠心病的预防和早期诊断及动态监测病情中,HCY、HS-CRP、LP(a)联合检测能更好地反映患者的病情程度,临床价值意义重大,可以作为评估冠心病患者病情程度监测的敏感指标。

关键词:同型半胱氨酸、血清超敏C- 反应蛋白、脂蛋白a;冠心病

Abstract:Objective To study the clinical significance of combined detection of homocysteine (HCY), hypersensitive C-reactive protein,hs-CRP (HS-CRP) and lipoprotein a (LP) in the diagnosis and treatment of coronary heart disease (CHD). Methods 126 patients with coronary heart disease were collected from October 2014 to May 2013, 42 patients with stable angina (SAP), 36 patients with unstable angina pectoris (UAP), 48 patients with acute myocardial infarction (AMI), and 88 healthy controls were randomly selected as control group. Serum HCY, LP (a), HS-CRP were measured. Results The levels of HCY, LP(a), HS-CRPin CHD group were significantly higher than those in control group (P < 0.05), and the control group was in normal range. The positive rate of AMI group and the positive rate of the detection of the positive rate of the three groups were gradually increased with the duration of the disease. Conclusion HCY、HS-CRP、LP(a)combined detection can better reflect the severity of patients and the clinical value of the disease, and...

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