急性脑梗死患者静脉溶栓后脑出血相关因素分析
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【摘要】 目的：分析急性脑梗死（ACI）患者静脉溶栓治疗后发生脑出血转化的相关因素。方法：选取本院收治的86例行静脉溶栓治疗的ACI患者，按照溶栓后是否发生脑出血转化将其分为病例组和对照组，比较两组差异，分析溶栓后脑出血转化的影响因素。结果：86例患者中有17例发生溶栓后脑出血转化;单因素分析显示，病例组发病到溶栓时间、溶栓前NIHSS评分、溶栓前血糖和溶栓后收缩压均高于对照组（P<0.05）;多因素分析显示，发病至溶栓时间长、溶栓前NIHSS评分高、溶栓前血糖高、溶栓24 h后收缩压高是溶栓后发生脑出血转化的危险因素（P<0.05）。结论：发病至溶栓时间长、溶栓前NIHSS评分高、溶栓24 h后收缩压高、血糖高可能是ACI静脉溶栓发生脑出血转化的危险因素，临床应给与高度重视。
【关键词】 急性脑梗死; 静脉溶栓; 脑出血性转化; 危险因素
【Abstract】 Objective：To analyze the related factors of cerebral hemorrhage transformation in patients with acute cerebral infarction（ACI）after intravenous thrombolysis.Method：A total of 86 patients with ACI treated by intravenous thrombolysis were selected.According to whether intracerebral hemorrhage transformation occurs after thrombolysis，they were divided into case group and control group.The differences between two groups were compared，and the influencing factors of intracerebral hemorrhage transformation after thrombolysis were analyzed.Result：In 86 patients，17 cases had intracerebral hemorrhage transformation after thrombolysis.Univariate analysis showed that the time from onset to thrombolysis，NIHSS score before thrombolysis，blood sugar before thrombolysis and systolic blood pressure after thrombolysis in case group were higher than those of control group（P<0.05）.Multivariate analysis showed that long time from onset to thrombolysis，high NIHSS sc...
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