大柴胡汤加减联合生长抑素对急性胰腺炎的临床疗效观察
摘要 目的:观察使用大柴胡汤加减联合生长抑素治疗急性胰腺炎前后,血中降钙素原(PCT)及C反应蛋白的变化情况,从而探讨大柴胡汤对急性胰腺炎患者血中降钙素原及C反应蛋白影响,并观察其临床疗效。方法:选取本院50例急性胰腺炎患者,随机分为2组,对照组15例使用生长抑素等常规药物治疗;治疗组35例,在对照组治疗的基础上,给予大柴胡汤加减经胃管注药。2组患者在确诊后即刻及治疗1 d、3 d、7 d时抽取静脉血,分别检测血降钙素原及C反应蛋白(CRP)含量,同时检测2组血常规白细胞计数及血淀粉酶检查。并分析2组生存率、重症患者肠鸣音恢复时间以及住院时间。结果:大柴胡汤加减联合生长抑素治疗组在PCT、CRP、白细胞计数及血淀粉酶方面与对照组相比,差异有统计学意义(P<0.05);在首次主动排便时间、住院时间之间差异存在明显统计学意义(P<0.01)。结论:大柴胡汤加减联合生长抑素可明显降低血PCT及CRP,调节胰酶分泌、抑制炎性反应因子,在治疗急性胰腺炎中有协同作用,是治疗急性胰腺炎的有效方法之一。
关键词 急性胰腺炎;大柴胡汤加减;PCT;CRP
The Effect of Dachengqi Decoction combined with Somatostatin in the Treatment of Acute Pancreatitis
Li Xiaomei, Lu Wei
(Inner Mongolia Medical University Affiliated Hospital, Hohehot 010030, China)
Abstract Objective:To observe the change of procalcitonin (PCT) and Creactive protein (CRP) in patients with acute pancreatitis after the treatment of Dachengqi decoction combined with somatostatin, then discussing the clinical curative effect of Dachengqi decoction on acute pancreatitis. Methods:Fifty cases of patients with acute pancreatitis in our hospital were randomly divided into two groups, with 15 cases given conventional treatment (eg:octreotide) in control group,and 30 cases given Dachengqi decoction by gastric tube in treatment group on the basis of the control group treatment. After treatment of 1 d, 3 d, 7 d, patients in two groups were immediately drew blood and detected the level of PCT and CR...
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