网状纤维染色在临床病理诊断中的应用及技术
[摘要] 网状纤维染色法是病理学传统的特殊染色方法之一，在临床病理学诊断及鉴别诊断中应用广泛。病理学诊断至今仍为临床多种肿瘤性疾病明确诊断及分型等的金标准，网状纤维染色法在多种肿瘤病理诊断中发挥重要的作用。网状纤维的组织改变在临床疾病病理诊断上有重要意义，如血液系统肿瘤、乳腺纤维上皮肿瘤、胃肠道间皮瘤、神经系统肿瘤等，但网状纤维在染色过程中易出现问题，如纤维着色不良、纤维退色、染色背景过深等。本文就网状纤维染色在临床病理诊断中的应用及技术作一综述。
[关键词] 网状纤维；染色；肿瘤；病理诊断
[中图分类号] R817.4 [文献标识码] A [文章编号] 1673-7210（2016）03（c）-0072-04
[Abstract] Reticular fiber staining is one of the classical method for special staining in pathology and has been wildly used in diagnosis and differential diagnosis of various diseases. Pathological diagnosis has been regarded as the golden standard in diagnosis and classification of many tumors， in which reticular fiber staining plays important roles. The changes of reticular fiber have important implications for clinical pathological diagnosis including hematological malignancies， fibro-epithelioma of breast， gastrointestinal mesothelioma， nervous system tumors， etc. However， in the process of reticular fiber staining， there may be some problems such as fiber coloring bad， fibrous degeneration and calcification， etc. This article reviews application of reticular fiber staining and common problems in the process of staining.
[Key words] Reticular fiber； Dyeing； Tumor； Pathological diagnosis
网状纤维是网状结缔组织内的一种纤维，由网状细胞所产生。网状纤维直径为0.2～1.0 μm，纤细而有分支，穿行于网状细胞体和细胞突之间，共同构成网状支架[1]。网状纤维普通HE染色难以辨认，缺乏弹性而有韧性，化学成分是网状蛋白，是一种特殊类型的胶原蛋白，在胶原纤维上包有一层特殊的糖蛋白，使网状纤维呈现嗜银性的特点，所以网状纤维又称为嗜银纤维，从而也利用网状纤...
|
== 试读已结束，如需继续阅读敬请充值会员 ==
|
|
本站文章均为原创投稿，仅供下载参考，付费用户可查看完整且有格式内容！
(费用标准：38元/2月，98元/2年，微信支付秒开通！) |
| 升级为会员即可查阅全文 。如需要查阅全文，请 免费注册 或 登录会员 |
|
