常规小剂量阿托伐他汀对急性冠脉综合征患者超C反应蛋白影响的观察
【摘要】 目的 探讨常规小剂量阿托伐他汀对急性冠脉综合征(ACS)患者血清超C反应蛋白(hs-CRP)的影响及意义。方法 将80例ACS患者随机分2组:常规治疗组(对照组),阿托伐他汀治疗组(观察组)。分别采用免疫比浊法测定hs-CRP测定这2组患者治疗前,治疗后4周,患者血清中hs-CRP的变化。结果 观察组治疗4周后hs-CRP与治疗前相比差异有统计学意义(P<0.05)。结论 常规小剂量阿托伐他汀治疗,可以显著降低血浆中炎症反应标志物hs-CRP的浓度,具有可观的治疗价值。
【关键词】 急性冠脉综合征;超敏C反应蛋白;阿托伐他汀
The observation of the effect of conventional low-dose atorvastatin on acute coronary syndrome patients with hs-CRP
XU Lin,XU Yi.
The Forth People’s Hospital of Taian,Shandong 271000,China
【Abstract】 Objective To investigate the effect and the significance of conventional low-dose atorvastatin on acute coronary syndrome (ACS) in patients with hs-CRP.Methods 80 cases of ACS patients were randomly divided into conventional therapy group (control group),atorvastatin treatment guoup (observation group).To measure changes of hs-CRP before treatment,4 weeks after treatment,by using immunotur bidimetric assay.Results 4 weeks after treatment, hs-CRP of the observation group compared with the pre-treatment differences were significont (P<0.05).Conclusion By the conventional low-dose atorvastatin therapy, can significantly reduce the plasma concentrations of hs-CRP, has considerationable therapeutic value.
【Key words】 Acute coronary syndrome; High-sensitivity C-reactive protein; Atorvastatin
作者单位:271000山东省泰安市第四人民医院
急性冠脉综合征(acute coronary syndrome,ACS),是一组由急性心肌缺血引起的临床综合征,以冠状动脉粥样硬化斑块破溃,继发完全或不完全闭塞性血栓形成为病理基础,包涵了不稳定型心绞痛(UA)、非ST段抬高的急性心肌梗死(NSTEMI)、ST段抬高的急性心肌梗死(STEMI)和猝死及不稳定型心绞痛。研究表明急性冠脉综合征(ACS)与斑块内炎症反应密切相...
|
== 试读已结束，如需继续阅读敬请充值会员 ==
|
|
本站文章均为原创投稿，仅供下载参考，付费用户可查看完整且有格式内容！
(费用标准：38元/2月，98元/2年，微信支付秒开通！) |
| 升级为会员即可查阅全文 。如需要查阅全文，请 免费注册 或 登录会员 |
|
