β2-微球蛋白与C-反应蛋白对Ⅳ型心肾综合征诊断及预后的判断意义
打开文本图片集
摘 要 目的:探讨β2-微球蛋白(β2-MG)与C反应蛋白(CRP)对Ⅳ型心肾综合征(CRS)的诊断及预后判断价值。方法:随机选取中老年Ⅳ型CRS确诊患者(A组)、慢性肾脏病(CKD)患者(B组)及健康体检者(C组)各30例;入院后查肾功能、β2-MG及CRP等,并对A组患者随访1年,据预后分为死亡组(D组)和生存组(E组)。结果:A组CRP及β2-MG水平显著高于B组和C组,LVEF显著低于B组和C组(P<0.05);D组CRP及β2-MG水平显著高于E组,LVEF显著低于E组(P<0.05)。CPR和β2-MG的ROC曲线下面积分别为0.698和0.697,敏感性96.7%和80.0%,特异性43.4%和66.7%。结论:β2-MG与CRP均是判断Ⅳ型CRS的较好生化指标。二者与LVEF联合判断有助于提高诊断准确性,并能更好地判断预后。
关键词 β2-微球蛋白 C-反应蛋白 慢性肾脏病 Ⅳ型心肾综合征
中图分类号:R541.61 文献标志码:B 文章编号:1006-1533(2018)07-0049-04
Significance of the detection of β2-microglobulin and C-reactive protein in the diagnosis and prognosis of type Ⅳ cardiorenal syndrome
TANG Te*
(Shaoyang No.1 Hospital, Hu’nan 422000, China)
ABSTRACT Objective: To investigate the significance of the detection of C-reactive protein (CRP) and β2-microglobulin
(β2-MG) in middle-aged patients with type Ⅳ cardiorenal syndrome (CRS). Methods: The randomly selected elderly patients with type Ⅳ CRS were divided as a group A, patients with chronic kidney disease (CKD) as a group B and healthy physical examination subjects as a group C with 30 cases each. Their renal function, β2- MG and CRP levels were detected. The patients in group A were followed up for a year and then divided into a death group (group D) and a survival group (group E) based on their prognosis. Results: The levels of CRP and ...
== 试读已结束,如需继续阅读敬请充值会员 ==
|
本站文章均为原创投稿,仅供下载参考,付费用户可查看完整且有格式内容!
(费用标准:38元/2月,98元/2年,微信支付秒开通!) |
升级为会员即可查阅全文 。如需要查阅全文,请 免费注册 或 登录会员 |