硫化氢与急性心肌梗死疗效及再灌注损伤的关系
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【摘要】 目的：探讨硫化氢与急性心肌梗死疗效及再灌注损伤的关系。方法：将2017年9月-2018年8月本院接收的急性心肌梗死患者100例作为观察组，将冠脉造影正常者100例设为对照组。测定硫化氢含量，将两组的硫化氢含量进行比对。结果：观察组的硫化氢含量为（28.89±3.76）μmol/L，低于对照组的（52.69±1.47）μmol/L，差异有统计学意义（P<0.05），且不同疗效组别对比硫化氢含量，差异均有统计学意义（P<0.05）;观察组患者溶栓治疗后2、4、6、12 h的硫化氢含量均低于溶栓治疗前，差异均有统计学意义（P<0.05）。结论：硫化氢含量能够对急性心肌梗死的病情严重程度以及临床疗效进行判断，同再灌注损伤存在一定的相关性。
【关键词】 硫化氢; 急性心肌梗死; 再灌注损伤
【Abstract】 Objective：To investigate the relationship between hydrogen sulfide and acute myocardial infarction（AMI）and reperfusion injury.Method：From September 2017 to August 2018，100 patients with acute myocardial infarction received by our hospital were selected as observation group and 100 patients with normal coronary angiography as control group.The content of hydrogen sulfide was determined and compared between the two groups.Result：The content of hydrogen sulfide in the observation group was（28.89±3.76）μmol/L，lower than（52.69±1.47）μmol/L in the control group，the difference was statistically significant（P<0.05）.In addition，the content of hydrogen sulfide in different treatment groups were compared，the differences were statistically significant（P<0.05），At 2，4，6 and 12 h after thrombolysis，the content of hydrogen sulfide in the observation group was lower than that before thrombolysis，the differences were statistically significant（P<0.05）.Conclusion：The content of hydrogen sulfide can judge the ...
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