盐酸米诺环素辅助牙周基础治疗对侵袭性牙周炎患者临床疗效的影响
[摘要]目的 探讨盐酸米诺环素辅助牙周基础治疗对侵袭性牙周炎患者临床疗效的影响。方法 选取本院2016年11月～2017年11月收治的64例患有侵袭性牙周炎患者，按随机分配的原则分为对照组和观察组，每组32例。对照组给予牙周基础治疗，观察组给予盐酸米诺环素辅助牙周基础治疗。比较两组的临床效果及治疗过程中的不良反应发生情况。结果 观察组的总有效率（90.63%）明显高于对照组（68.76%）（P<0.05）。与治疗前比较，两组治疗后的探诊出血指数（BI）、牙周探诊深度（PD）、附着水平（AL）水平均明显降低，且观察组上述指标的降低幅度显著大于对照组（P<0.05）。两组的不良反总应发生率比较，差异无统计学意义（P>0.05）。结论 盐酸米诺环素辅助牙周炎基础治疗侵袭性牙周炎的临床效果显著，无明显不良反应，安全性好，值得临床推广。
[关键词]盐酸米诺环素；侵袭性牙周炎；基础治疗；临床疗效
[中图分类号] R781.4+2 [文献标识码] A [文章编号] 1674-4721（2018）12（b）-0113-03
[Abstract] Objective To investigate the effect of Minocycline Hydrochloride assisting periodental basic treatment on the clinical curative effect of patients with aggressive periodontitis. Methods All of 64 patients with aggressive periodontitis admitted into our hospital from November 2016 to November 2017 were selected and they were divided into the control group and the observation group according to the principle of random distribution， and each group had 32 cases. The control group was treated with periodontal basic therapy， while the observation group was given Minocycline Hydrochloride assisting periodental non-surgical treatment. The clinical effect and the incidence of adverse reactions during treatment between the two groups were compared. Results The total effective rate of the observation group （90.63%） was significantly higher than that of the control group （68.76%） （P<0.05）. Compared with those before treatment， the level of bleeding index （BI）， the depth of periodont...
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