氟西汀合并抗精神病药物治疗具有强迫症状的精神分裂症的疗效研究
摘要：目的 研究氟西汀合并抗精神病药物治疗具有强迫症状的精神分裂症的疗效。方法 选取我院收治的患有强迫症状的精神分裂患者60例，随机分为对照组和观察组，每组各30例，均采用抗精神病药物治疗，观察组在此基础之上加入氟西汀治疗，治疗1个月后观察对比两组疗效、强迫症状量表（Y-BOCS）等，同时记录不良反应的发生情况。结果 观察组的总有效率显著高于对照组，差异具有统计学意义（P<0.05）。治疗1个月后，治疗组的Y-BOCS评分低于对照组，差异具有统计学意义（P<0.05）。结论 在治疗有强迫症状的精神分裂患者时应用氟西汀联合抗精神病药物，可以有效改善精神分裂患者的强迫症状及精神症状，有助于提高此类患者的生活质量。
关键词：氟西汀；抗精神病药物；强迫症状；精神分裂症
中图分类号：R749.3 文献标识码：A 文章编号：1006-1959（2017）16-0087-02
Efficacy of Fluoxetine in Combination with Antipsychotic Drugs in the Treatment of Schizophrenia with Obsessive Symptoms
ZHAO Liang，LUO Yi，TANG Sheng，DU Jie
（Department of Psychiatry，Six Ward，Wuhan Excellent Hospital，Wuhan 430023，Hubei，China）
Abstract：Objective To study the efficacy of fluoxetine combined with antipsychotic treatment of schizophrenia with obsessive-compulsive symptoms. Methods We selected 60 cases of schizophrenic patients with obsessive-compulsive symptoms in our hospital.They were randomly divided into the control group and the observation group，30 cases in each group，all of them were treated with antipsychotic drugs，the observation group was treated with fluoxetine on the basis of this treatment.After 1 month treatment，the curative effect of the two groups and obsessive compulsive disorder scale（Y-BOCS）were observed and compared，and the adverse reactions were recorded.Results The total effective rate of observation group was significantly higher than the control group，the difference was statistically significant（P<0.05）.After 1 month of treatment，Y-BOCS...
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