白芷的有效成分提取、药理作用及临床应用研究进展
[摘要] 白芷来源为伞形科植物，具有散风除湿、通窍止痛、消肿排脓的作用，临床上广泛用于治疗眉棱骨痛、鼻塞、牙痛、疮疡肿痛等症，是中医临床的常用药，主产于我国四川、杭州等地，其有效成分十分复杂，主要为香豆素类和挥发油。本文就白芷的化学成分、提取工艺、药理作用及安全性评价等几个方面，综述了白芷近年来的研究现状，表明白芷具有镇痛、抗菌、平喘、兴奋运动和呼吸中枢、光毒性等方面的药理作用，为白芷的进一步研究提供依据。但白芷的部分作用机制还未明确，尤其在组方中的作用机制尚不清楚，有待于进一步研究。
[关键词] 白芷；提取工艺；药理作用；临床应用
[中图分类号] R284.1 [文献标识码] A [文章编号] 1673-7210（2014）11（a）-0159-05
Research progress of Angelica dahurica for extracting effective components， pharmacological action and clinical application
ZHU Yixin1 LI Baoli1 MA Hongsheng2 LIU Yongxian1
1.Yan′an University， Shaanxi Province， Yan′an 716000， China； 2.The Affiliated Hospital of Yan′an University， Shaanxi Province， Yan′an 716000， China
[Abstract] Angelica dahurica is source of umbrelliferae plant. It has the funtion of eliminating wind and dampness. It also has the effect of relieving stuffy nose and wind the pain， swelling， empyema. In clinical practice， it is applied to traeting nasal obstruction， leucorrhea， sores and carbuncles. It is the traditional Chinese medicine clinical commonly used medicines. Angelica dahurica is mainly produced in Sichuan and Hangzhou of China. Its chemical constitution are very complex. However， its main components are coumarin and volatile oil. This paper summarizes the research status in recent years， starting from the chemical composition， extraction process， pharmacological effects， safety evaluation and other aspects in Angelica dahurica. All of these indicate that Angelica dahurica has phramacological function of relievin...
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