西安地区儿童败血症主要病原菌分析
摘 要 目的：研究西安地区儿童败血症主要病原菌。方法：用BacT /ALERT3D全自动血培养仪对200例儿童血培养阳性检查结果进行分析。结果：①儿童败血症主要病原菌为革兰阳性菌（82.6%）；其次为革兰阴性菌（12.0%）；真菌感染仅为3.0%。②革兰阳性菌感染的败血症以葡萄球菌为主，占革兰阳性菌感染败血症的95.0%，其中以金葡和表葡最为常见。对青霉素耐药率为90%以上，对万古霉素耐药率为0。③革兰阴性菌感染的败血症以肠杆菌科为主（51.2%），ESBLs阳性率为40.4%；革兰阴性非发酵菌占革兰阴性菌感染败血症的47.0%，以铜绿假单胞菌常见。结论：细菌的耐药性已成为临床治疗的棘手问题，因此应根据药敏实验结果合理用药，减少细菌耐药的发生。
关键词 儿童 败血症 病原菌 耐药
ABSTRACTOBJECTIVE:Research on primary pathogenic bacteria of children septicemia in Xi"an. METHODS: Tested 200 cases of children septicemia by BacT/ALERT3D automatic blood culture analyzer.RESULTS:①The main pathogenic bacteria in children septicemia was gram-positive(G+)bacteria，82.6%；next was gram-negative(G-)bacteria，12.0%；fungous only accounted for 3.0% of infections.②95.0% of septicemia-causing G+ bacteria was Staphylococcus，among which Staphylococcus aureus and Staphylococcus epidermidis were most common.90% of pathogenic bacteria were resistive to penicillin and all of them were sensitive to vancomycin.③The main septicemia-causing G- bacteria was enteric bacilli，51.2%，and 40.4% of that was ESBLs positive.47.0% of septicemia-causing G- bacteria was Nonfermenters and Pseudomonas aeruginosa was most common.CONCLUSION:The drug resistance of pathogenic bacteria had become an intractable problem in clinical medicine.Appropriate medication based on drug-sensitivity results should put into administration to reduce the rate of drug resistance.
Key Wordchildsepticemiapathogenic bacteriadrug resistance
儿童败血症是儿童期常见的严重的细菌感染性疾病,其发病率也与患者的敏感性、地区、...
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