广州市售水产品副溶血弧菌和溶藻弧菌的耐药性评估
摘要 [目的]研究广州市售水产品中副溶血弧菌和溶藻弧菌的耐药性情况。[方法]采用Kirby-Bauer纸片扩散法检测从水产品中分离的87株副溶血弧菌和118株溶藻弧菌对水产养殖业中常用的18种抗生素的耐药情况。[结果]水产品中的副溶血弧菌和溶藻弧菌均对万古霉素、克林霉素以及青霉素类抗生素有明显抗性，多重耐药比例达100%，溶藻弧菌的多重耐受现象较为突出。[结论] 广州市售水产品中的副溶血弧菌和溶藻弧菌具有多种抗生素抗性，且多重耐药情况突出。
关键词 副溶血弧菌；溶藻弧菌；耐药性；多重耐药
中图分类号 S948 文献标识码 A 文章编号 0517-6611（2017）28-0074-04
Abstract [Objective] To investigate the drug resistance of Vibrio parahemolytics and Vibrio alginolyticus in aquatic products from Guangzhou retail markets. [Method] KirbyBauer disk diffusion method was used to detect the antibiotic resistance of 87 isolates of V. parahemolytics and 118 isolates of V. alginolyticus in aquatic products to 18 kinds of antibiotics widely used in aquaculture industry. [Result] Both V. parahemolytics and V. alginolyticus were resistant to vancomycin， clindamycin and penicilins. All the isolates exhibited multidrug resistance， while V. alginolyticus isolates showed outstanding multiple antibiotic resistance. [Conclusion] V. parahemolytics and V. alginolyticus in aquatic products from Guangzhou retail markets were resistant to many kinds of antibiotics， they also exhibited complex multidrug resistance.
Key words Vibrio parahemolytics；Vibrio alginolyticus；Drug resistance；Multidrug resistance
副溶血弧菌是一种革兰氏阴性嗜盐细菌，主要分布于海水、海底沉積物以及鱼、虾、贝类等海产品中，不仅是水产养殖业的重要病原菌，而且是人类主要的食源性致病菌之一[1-3]。我国是副溶血弧菌引发食物中毒的高发地区，由该病原菌感染引发的急性肠胃炎占细菌性食物中毒的首位，在某些沿海城市比例高达60%以上[4-5]。溶藻弧菌虽然是水生环境中的优势菌种，同样会引起水生动物感染，但其对人类的致病性...
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