腹腔镜治疗对急性化脓性阑尾炎患儿血清炎症因子及免疫功能的影响
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【摘要】 目的：探究腹腔镜手术对急性化脓性阑尾炎患儿血清炎症因子和免疫功能的影响。方法：选取2016年3月-2018年3月经治的急性化脓性阑尾炎患儿120例，采用随机数字表法将患儿分为观察组与对照组，各60例。对照组采取开腹阑尾切除术，观察组采取腹腔镜手术治疗。记录两组手术相关指标及术后并发症，检测两组手术前后血清炎症因子及免疫功能变化情况。结果：观察组术中出血量、住院时间及术后首次排气时间均少于对照组（P<0.05）;术后1周，观察组IL-6、IL-8、CRP水平均明显低于对照组，IgM、IgG水平均明显高于对照组（P<0.05）;观察组术后并发症发生率为3.33%，显著低于对照组的15.00%（P<0.05）。结论：腹腔镜手术治疗急性化脓性阑尾炎，能够减少患儿术中出血量，缩短住院时间，降低术后炎症因子的应激表达和免疫功能的损伤，且术后并发症少，安全性高。
【关键词】 腹腔镜手术; 急性化脓性阑尾炎; 炎症因子; 免疫功能
【Abstract】 Objective：To investigate the effects of laparoscopic surgery on serum inflammatory factors and immune function in children with acute suppurative appendicitis.Method：A total of 120 children with acute suppurative appendicitis who underwent surgery from March 2016 to March 2018 were eolled.The patients were divided into observation group and control group by random number method，with 60 cases in each group.The control group underwent open appendectomy and the observation group underwent laparoscopic surgery.The two groups of surgical related indexes and postoperative complications were recorded.The changes of serum inflammatory factors and immune function before and after operation were detected.Result：The amount of bleeding，length of hospital stay and the first exhaust time of the observation group were lower than those of the control group（P<0.05）.At 1 week after operat...
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