NBI联合碘染在早期食管癌及癌前病变中的临床应用
摘要：目的 探讨NBI联合碘染在早期食管癌及癌前病变临床诊断中的应用价值。方法 选取60例于2012年11月～2015年8月行内镜下活检并经过病理诊断确诊的早期食管癌及癌前病变患者进行研究，并根据诊断方法随机分成对照组（30例，常规内镜）和观察组（30例，NBI结合碘染），对比两组的诊断结果。结果 观察组的病变轮廓清晰度显著优于对照组，且观察组对低级别上皮内瘤变的检出率为100%，和对照组的76.92%比较，差异显著，具有统计学意义（P<0.05）。两组病变发生部位均以食管中段为主，且食管左侧壁发生病变较多。结论 采用NBI联合碘染对早期食管癌及癌前病变进行诊断可以提高检出率，具有较高的临床应用价值。
关键词：NBI；碘染；早期食管癌；癌前病变
Abstract：Objective To investigate the application value of NBI in the diagnosis of early esophageal cancer and precancerous lesions. Methods Selected 60 cases from November 2012 to August 2015，and the early esophageal cancer and precancerous lesions diagnosed by pathological diagnosis by endoscopic biopsy was studied，the diagnosis was randomly divided into control group （30 cases， conventional endoscopy） and observation group （30 cases， NBI combined with iodine staining），contrast two groups of diagnosis results.Results The lesions of the observation group were significantly better than the control group， The detection rate of Low grade intraepithelial neoplasia was 100% in the observation group ， and the control group was 76.92%， the difference was statistically significant （P<0.05）.The lesions in the two groups were mainly in the middle of the esophagus，the left side wall of esophagus is more pathological changes.Conclusion NBI combined with iodine staining in early esophageal cancer and precancerous lesions can improve the detection rate of diagnosis， and it has a high clinical value.
Key words：NBI； Iodine staining；Early esophageal cancer；Precancerous lesions
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