前列地尔联合血必净治疗重症急性胰腺炎临床疗效观察
摘要：目的 探討前列地尔联合血必净治疗重症急性胰腺炎疗效。方法 重症急性胰腺炎患者60例，按随机数字表法分为对照组、实验组，各30例。对照组选择常规方案+血必净治疗，实验组在对照组治疗基础上加用前列地尔。观察两组病例腹痛缓解时间、发热持续时间、胃肠功能恢复时间、血清淀粉酶恢复时间、白细胞总数恢复时间、平均住院时间、并发症发生率、中转手术率及总有效率。结果（1）腹痛缓解时间：对照组5.07±0.87 天，实验组4.30±0.99 天;发热持续时间：对照组5.27±0.79 天，实验组4.47±0.97天;胃肠功能恢复时间：对照组7.03±1.19天，实验组6.23±0.94天;血清淀粉酶恢复时间：对照组7.47±1.04 天，实验组6.80±1.16天;白细胞恢复时间：对照组9.40±0.77 天，实验组8.70±0.84天;平均住院时间：对照组27.20±2.99天，实验组23.15±2.69天，两组比较差异有统计学意义（P<0.05）;（2）实验组并发症发生率、中转手术率、总有效率与对照组间差异有统计学意义（χ2 =4.36、4.32、5.46 P <0.05）。结论 前列地尔联合血必净治疗重症急性胰腺炎疗效确切，安全性高，值得临床推广应用。
关键词：前列地尔;血必净;重症急性胰腺炎
[Abstract] Objective To explore the efficacy of alprostadil combined with Xuebijing in the treatment of severe acute pancreatitis. Method A total of 60 cases of severe acute pancreatitis were selected，and randomly divided into a control group and an experimental group with 30 cases in each group. The control group was treated with the conventional scheme plus Xuebijing，and the experimental group with alprostadil on the basis of the control group treatment. The abdominal pain relief time，the duration of fever，the time of gastrointestinal function recovery，the time of serum amylase recovery，the time of white blood cell recovery，the average length of hospital stay，the complication rate，the transit operation rate and the total effective rate were collected. Results（1）The time of abdominal pain relief time：5.07 ± 0.87 days in the control group，and 4.30 ± 0.99 day...
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