少腹逐瘀汤对原发性痛经患者雌激素、前列腺素E2及临床疗效的影响
摘要 目的：探讨少腹逐瘀汤对原发性痛经患者雌激素（E2），前列腺素E2（PGE2）水平及临床疗效的影响。方法：选取原发性痛经患者90例，随机分为对照组和观察组，每组45例，对照组患者给予痛经宝颗粒，观察组患者给予少腹逐瘀胶囊，治疗结束后，对所有患者的E2、孕激素（P）P、PGE2、疼痛程度临床疗效进行检测并比较。结果：与治疗前比较，治疗后2组患者E2、疼痛程度积分均下降，P、PGE2水平均升高（P<0.05）；与对照组比较，观察组患者E2、疼痛程度积分较低，P、PGE2水平较高（P<0.05），观察组患者的治疗总有效率较高（P<0.05）。结论：少腹逐瘀汤能够降低原发性痛经患者E2、疼痛程度积分，升高P、PGE2水平，具有较好的临床效果。
关键词 少腹逐瘀汤；原发性痛经；雌激素；前列腺素
Abstract Objective：To investigate the effects of t Shaofu Zhuyu Decoction in the treatment of primary dysmenorrhea patients on estrogen （E2）， prostaglandin E2 and clinical efficacy. Methods：A total of 90 patients with primary dysmenorrhea from Beijing Daxing District Hospital of Integrated Chinese and Western Medicine were selected from January 2014 to December 2015 and randomly divided into the control group and the experiment group with 45 cases in each group. The control group was treated with Tongjingbao Granules and the experiment group was treated with Shaofu Zhuyu Decoction. E2， progestational hormone P （P）， PGE2， degree of pain and clinical efficacy were compared before and after treatment. Results：Compared with the condition before treatment， E2， the degree of pain scores of two groups of patients were decreased， P and PGE2 levels were significantly increased （P<0.05）； Compared with the control group， E2 and the degree of pain scores were lower， and P and PGE2 levels were higher of the patients in the experimental group （P<0.05）. The total effective rate of treatment group was higher （P<0.05）. Conclusion：Shaofu Zhuyu De...
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