氯吡格雷联合阿司匹林治疗急性心肌梗死的临床效果观察
【摘 要】目的：探讨氯吡格雷联合阿司匹林治疗急性心肌梗死的临床效果。方法：收集2016年9月至2018年3月入院的96例急性心肌梗死患者，随机分为试验组与对照组各48例，对照组患者给予阿司匹林治疗，试验组患者给予氯吡格雷联合阿司匹林治疗，比较两组患者血管再通率、血管再闭塞率、心血管事件发生率、治疗后血小板聚集率、凝血指标及左心室射血分数。结果：试验组患者血管再通率高于对照组，血管在闭塞率、心血管事件发生率低于对照组，存在明显差异（P<0.05）；治疗后血小板聚集率低于对照组，左心室射血分数高于对照组，存在显著性差异（P<0.01）；治疗后两组凝血指标无统计学差异（P>0.05）。结论：急性心肌梗死患者的抗血小板治疗中，氯吡格雷联合阿司匹林抗血小板效果更好，有效减少心血管事件的发生，疗效确切，值得推广应用。
【关键词】氯吡格雷；阿司匹林；急性心肌梗死；抗血小板
[Abstract] Objective：To explore the clinical effect of clopidogrel combined with aspirin in the treatment of acute myocardial infarction.Method：96patients with acute myocardial infarction admitted from September2016to March2018were randomly divided into48cases in the experimental group and the control group.The patients in the control group were treated with aspirin.The patients in the test group were treated with clopidogrel and aspirin.The rate of repassage， reocclusion and the incidence of cardiovascular events in the two groups were compared.And platelet aggregation rate， coagulation index and left ventricular ejection fraction after treatment.Result：The rate of blood vessel repassage in the experimental group was higher than that of the control group.The incidence of vascular occlusion rate and cardiovascular events was lower than that of the control group （P<0.05）.After treatment， the platelet aggregation rate was lower than that of the control group.The left ventricular ejection fraction was higher than the control group （P<0.01）； after treatment， the blood coa...
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