消积饮维持治疗不同病理类型晚期非小细胞肺癌临床观察
【摘 要】目的：探讨消积饮维持治疗对不同病理类型晚期非小细胞肺癌（NSCLC）的疗效。方法：根据纳入标准选入52例晚期NSCLC患者，予每天100ml消积饮维持治疗直至疾病进展，观察消积饮维持治疗对不同病理类型晚期NSCLC的疗效及生存时间。采用Kplan- Meier生存分析法比较组间无进展时间、中位生存时间的差异。结果：入组患者鳞癌组24例，54.2%（13/24），非鳞癌组共26例，病灶稳定率为30.8%（8/26），鳞癌组与非鳞癌组病灶稳定率有显著性差异。鳞癌组中位无进展时间为5.1个月，非鳞癌组中位无进展时间为3.0个月，两组之间差异有显著性。鳞癌组中位生存时间为6.4个月，非鳞癌组中位生存时间为3.1个月，两组之间差异有显著性。结论：消积饮维持治疗方案对于不同病理类型晚期非小细胞肺癌患者均有效，且肺鳞癌患者生存期优于非鳞癌患者。
【关键词】消积饮；晚期非小细胞肺癌 ；病理类型；维持治疗
【中图分类号】R 734.2 【文献标识码】A 【文章编号】1004- 7484（2012）05- 0120- 02
Observation on efficacy of maintenance therapy with Xiaoji- decoction in patients with advanced non- small cell lung cancer of differential pathological types
CHAI Xiao- shu Liu- ning（Department of Oncology, Guangdong Hospital of TCM, Guangzhou 510006, China）
【Abstract】 objective：To evaluate efficacy of maintenance therapy with Xiaoji-decoction in patients with advanced non-small cell lung cancer of differential pathological types.Methods：Fifty-two patients with advanced NSCLC were administered with 100ml oral dose of Xiaoji-decoction once daily until disease progression. Median survival time and progression-free survival were evaluated regularly by Kplan-Meier analysis，variations of the disease stable rate in differential groups type were assessed by the analysis 0f chisquare-test.Results：The disease stable rate was 54.2%（13/24）36 in the squamous carcinoma group and 30.8%（8/26）in the non-squamous carcinoma group(P=0.00). Progression-free survival was 5.1 months and 3.0 months (P=0....
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