腹腔镜手术联合甲氨喋呤治疗异位妊娠的疗效观察

材料写作网    时间: 2020-06-15 04:28:31     阅读:次

【摘要】 目的 探讨腹腔镜手术联合甲氨喋呤治疗异位妊娠的疗效。方法 将2010年5月至2010年10月在广州市妇婴医院确诊为异位妊娠的56例患者随机分成两组。观察组：45例，采用腹腔镜手术联合甲氨喋呤(MTX)，对照组：11例，单采用腹腔镜手术。比较两组患者治愈成功率、治疗前、后血βHCG下降值及两种手术的住院时间。结果 两组患者治愈成功率比较差异无统计学意义(P>005),观察组血βHCG降至正常的时间明显快于对照组(P<005)，两组术后的输卵管通水情况及两组住院天数比较差异无统计学意义(P>005)。 结论 采用腹腔镜手术联合甲氨喋呤治疗异位妊娠能更快、更有效地抑制滋养细胞增长，提高疗效，缩短治疗时间，减少治疗费用。

【关键词】

甲氨喋呤；异位妊娠；腹腔镜；血β HCG值

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Clinical observation of efficacy of laparoscopic surgery combining with Methotraxate in ectopic pregnancy

YANG Hongmei， ZHU Yanhong， HUANG Xiaofan，et al.Guangzhou Women and Childrens Medical Center, Guangzhou, 510180,China

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【Abstract】 Objective

To investigate the efficacy of laparoscopic surgery combining with Methotrexate (MTX) in ectopic pregnancy Methods 56 patients who were diagnosed of ectopic pregnancy in Guangzhou Maternal and Infant Hospital from May to October in 2010 were randomly divided into two groups The patients in observation group (n=45) received the treatment of laparoscopic surgery combining with MTX and those in control group received laparoscopic surgery only.Results Those were compared between two groups，including the cure rate，decrease of serum βHCG before and after the surgery and the hospitalization time.There was no significant statistical difference of cure rate between two groups (P>005) The time of serum βHCG decrease to normal level of observation group was faster than that of control group (P<005)The tubal water situation and hospitalization time were no stat...

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