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1599例前列腺液标本支原体感染检测及药敏结果分析

材料写作网    时间: 2020-09-12 04:05:29     阅读:

【摘要】目的:回顾本地区男性泌尿生殖道患者感染解脲支原体(UU)、人型支原体(MH)的分布状况,了解支原体对12种抗生素体外药物敏感试验的现状。方法:对1599例男性泌尿生殖道感染患者前列腺液标本进行支原体(Uu、MH)培养及药敏试验。结果:1599例检测标本中,总感染率为2308%,单纯UU阳性277例(7507%),UU-Mh阳性81例(2195%),单纯Mh阳性11例(298%)。MH对强力霉素(DOX)、交沙霉素(JOS)、美满霉素(MIN)全部敏感,UU对JOS、MIN、DOX、环酯红霉素(ECC)、克拉霉素(CLA)均非常敏感,UU-MH混合感染的耐药率明显高于单纯UU或MH感染。结论:临床治疗支原体感染时应尽量根据药敏结果选择敏感药物,DOX、MIN和JOS可作为本地区临床经验用药的首选药物。

【关键词】男性;解脲支原体;人型支原体;药物敏感性实验

【Abstract】Objectives: To review the incidences of urogenital tract infection caused by ureaplasma urealyticum (UU) and mycoplasma hominis (MH) and their susceptibilities to 12 antibiotic agents. Methods: UU and MH were cultured and their drug susceptibilities from 1,599 patients with urogenital tract infections were statistically analyzed. Results: The overall positive incidence of gential mycoplasmas was 23.08%. The most common pattern was UU mono-infection (75.07%); the UU-MH co-infection pattern ranked second (21.95%) and MH mono-infection was lowest (2.98%). However, a significantly higher infection rate by genital mycoplasmas was found in young men (age range: 21-50 years). Overall, MH complete susceptibility to doxycycline (DOX), josamycin (JOS) and minocycline (MIN), while UU had high susceptibility rates to JOS, MIN, DOX, erythromycin cyclocarbonate (ECC) and clarithromycin (CLA). The resistance rates of UU-MH-mixed isolates to most of drugs were significantly higher than those of UU- or MH-single isolates. Conclusions: The laboratory screening and antimicrobial susceptibility testing for gen...

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