HIV/HBV/HCV共感染者CD4+\CD8+T淋巴细胞计数的对比分析
[摘要] 目的 研究HIV/HBV/HCV共感染者外周血CD4+、CD8+T淋巴细胞计数变化，探讨共感染对HIV感染进程及患者机体免疫功能的影响。 方法 对75例HIV共感染样本进行外周血CD4+、CD8+T淋巴细胞计数测定并进行分析。 结果 4组的CD4+T淋巴细胞计数比较差异无统计学意义（P＞0.05）；4组的CD8+T淋巴细胞计数及CD4+/CD8+比较差异有统计学意义（P＜0.05）。 结论 共感染会影响患者外周血CD8+T淋巴细胞计数及CD4+/CD8+比值，HIV/HBV/HCV三重感染患者的CD8+T淋巴细胞计数较其他组高。
[关键词] HIV；HBV；HCV；共感染；CD4；CD8
[中图分类号] R512.91[文献标识码] A[文章编号] 1674-4721（2014）03（c）-0103-03
Comparative analysis of CD4+,CD8+ T lymphocyte count in co-infected patient with HIV/HBV/HCV
CHEN Shang-liang1 LI Jia-qi2 LI Jie-ming1 YU Wen-chao1 LU Shao-fen1 LUO Huai-xue1 XIAO Su-liu2
1.Blood Center of Zhaoqing City in Guangdong Province,Zhaoqing526020,China;2.Yangchun Prison Hospital in Guangdong Province,Yangchun529600,China
[Abstract] Objective To study the change of of CD4+,CD8+ T lymphocyte count in co-infected patient with HIV/HBV/HCV and to investigate the influence of co-infection on HIV infection process and the immune function of patient.Methods 75 peripheral blood samples with HIV co-infection were selected,CD4+,CD8+ T lymphocyte count was tested and analysed.Results CD4+ T lymphocyte count in four groups was compared,with no statistical difference(P＞0.05).CD8+ T lymphocyte count and CD4+/CD8+ ratio in four groups was compared respectively,with statistical difference(P＜0.05).Conclusion Peripheral blood CD8+ T lymphocyte count and CD4+/CD8+ ratio are changed in co-infected patient,CD8+ T lymphocyte count of HIV/HBV/HCV co-infected group is highter than other three groups.
[Key words] HIV;HBV;HCV;Co-infection;CD4;CD8
艾滋病是一种严重危害人类健康的传染病，目前该病已波及全球200多个国家和地区，感染者总数...
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