硫酸镁早期干预急性胆管炎的疗效分析
doi：10.3969/j.issn.1007-614x.2013.23.14
摘 要 目的：观察早期应用硫酸镁对急性胆管炎的疗效。方法：采用回顾性研究，选择急性胆管炎患者为研究对象，早期应用硫酸镁为观察组143例，141例未用硫酸镁为对照组。结果：观察组在24小时以后疼痛缓解率、白细胞降低率、体温降低率、排便率较对照组明显增高；急诊手术率较对照组明显降低。急性胆管炎发病距给药时间越短，硫酸镁对疼痛缓解率越高。结论：对急性轻型胆管炎早期硫酸镁干预，能够缓解患者症状，减轻痛苦；能够降低急诊手术率。考虑与应用硫酸镁能够缓解Oddi括约肌痉挛，解除胆管下端梗阻，控制急性胆管炎病情发展有关。急性胆管炎发病距给药时间越短，硫酸镁缓解Oddi括约肌痉挛进而缓解急性胆管炎的效果越明显。
关键词 硫酸镁 急性胆管炎 Oddi括约肌
Abstract Objective：let’s observe how magnesium sulfate can effect on cholangitis in the early stage.Method：By adopting retrospective study，143 cases of early application of magnesium sulfate were chosen as the observation team while 141 patients who were untreated with magnesium sulfate as a control group.Result：In observation group after 24-48 hours，the rate of pain relief，temperature dropping，leukocyte reducing and the status of defecation is significantly higher than the control team；while the happening rate of emergency surgery is lower than the control team（P<0.01）.The shorter the magnesium sulfate is injected，the faster the pain relief will be effected.Conclusion：Choosing magnesium sulfates to intervene early on acute cholangitis can alleviate the symptoms and reduce the happening rate of emergency surgery. Hence， we believe magnesium sulfate may alleviate the Oddi sphincter spasm，remove obstruction of the lower bile duct and control the development of acute cholangitis.The shorter the magnesium sulfate is injected，the faster the pain relief will be effected.
Key words Magnesium sulfate；Acute cholangitis；Oddi...
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