绞股蓝黄芪保健茶对免疫功能的影响
摘 要：研究绞股蓝黄芪保健茶对小鼠免疫功能的影响。将200只清洁级ICR雌性小鼠，按体重分成免疫5大组，每组随机分成4小组，每小组10只；按人日推荐用量的5倍、10倍、30倍，分别设0.415、0.830、2.490g/kgBw 3个剂量组和蒸馏水对照组。小鼠每天按20mL/kgBW连续灌胃30d后，分别测定小鼠的体重、脏器指数、细胞免疫功能、体液免疫功能、单核-巨噬功能以及NK细胞活性。结果表明：样品高剂量组小鼠淋转OD差值、抗体积数、溶血空斑数和碳廓清吞噬指数a都明显高于对照组，经统计，差异均有统计学意义（p<0.05）；高剂量的样品对小鼠的免疫功能有明显的增强作用。
关键词：绞股蓝；黄芪；茶叶；免疫力
中图分类号 R151 文献标识码 A 文章编号 1007-7731（2018）08-0048-04
Effect of Gynostemma Astragalus Health Tea on Immune Function
Yang Sufang1 et al.
（1College of Pharmacy，Fujian University of Chinese Medicine，Fuzhou 350108，China）
Abstract：To study the effect of gynostemma astragalus health tea on immune function in mice. 200 clean grade ICR female mice were divided into 5 groups according to their body weight. Each group was randomly divided into 4 groups with 10 in each group. According to the recommended daily dosage of 5 times，10 times，and 30 times，0.415 ，0.830 and 2.490g/kgBw were set with distilled water control group. The mice were continuously fed with 20 mL/kg BW daily for 30 days. The body weight，organ index，cellular immune function，humoral immune function，monocyte-macrophage function and NK cell activity were measured. The results showed that the OD value，anti-volume number，hemolytic plaque number，and carbon clearance phagocytic index a of the high-dose mice in the high-dose group were significantly higher than those in the control group. Statistically，the differences were statistically significant（p<0.05）. High-dose samples have a significant enhancement of immune function in mice.
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