急性肺栓塞患者血D—二聚体、B型钠尿肽、肌钙蛋白I、C反应蛋白的研究
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[摘要] 目的 探讨急性肺栓塞(APE)患者血D-二聚体(DD)、B型钠尿肽(BNP)、肌钙蛋白I(TnI)和C反应蛋白(CRP)浓度变化与临床意义。 方法 收集本院2013年6月~2015年6月收治的APE患者58例为实验组,同一时期随机选取50名医院体检中心健康体检者为对照组。分别进行DD、BNP、TnI、CRP浓度检测;比较各组DD、TnI、BNP、CRP浓度。 结果 实验组DD、BNP、TnI、CRP浓度较对照组高,两组比较差异有统计学意义(P<0.01)。实验组DD、BNP、TnI、CRP浓度较治疗有效组高,两组比较差异有统计学意义(P<0.01)。实验组DD、BNP、TnI、CRP浓度均值较治疗无效组高,两组比较差异无统计学意义(P>0.05)。 结论 联合检测DD、BNP、TnI、CRP浓度对APE患者诊断、病情判断、疗效评价及预后的发展具有重要的临床意义。
[关键词] 急性肺栓塞;D-二聚体;B型钠尿肽;肌钙蛋白I;C反应蛋白
[中图分类号] R543.3+1 [文献标识码] A [文章编号] 1674-4721(2016)01(c)-0028-03
[Abstract] Objective To explore the concentration change and clinical meaning of DD,BNP,TnI and CRP in acute pulmonary embolism(APE) patients. Methods 56 APE patients from June 2013 to June 2015 of our hospital were selected as experimental group,and 50 healthy examined people at the same period of physical examination center were selected as control group.The concentration of DD,BNP,TnI and CRP was compared respectively.After treatment for 2 weeks, the concentration of DD,BNP,TnI and CRP in APE patients were compared with experimental group. Results The concentration of DD,BNP,TnI and CRP in experimental group was higher than that of control group respectively,and the difference was statistical significance(P<0.01).The concentration of DD,BNP,TnI and CRP in experimental group was higher than that of effectively treatment group respec...
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