多西他赛联合氟尿嘧啶治疗进展期胃癌临床疗效分析
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[摘要] 目的 通过对多西他赛联合氟尿嘧啶治疗进展期胃癌的临床治疗情况，观察其疗效及安全性。方法 整群选取2012年1月”2015年1月入该院治疗的168例进展期胃癌患者，随机分为治疗组、对照组，各84例。治疗组采用多西他赛联合氟尿嘧啶进行化疗，对照组则用多西他赛联合替吉奥进行化疗。两组患者均以3周为1个疗程，至少进行2疗程的化疗。治疗结束后观察两组患者的体能改善情况、近期临床疗效以及化疗发生不良反应的情况。结果 两组患者化疗近期有效率比较差异无统计学意义（P>0.05），但治疗组体能改善率（83.34%）明显高于对照组（45.24%），两组差异有统计学意义（P<0.05）。结论 多西他赛联合氟尿嘧啶治疗进展期胃癌在保证治疗效果的同时，能够较少的影响患者体能状态有临床应用价值。
[关键词] 多西他赛；氟尿嘧啶；进展期胃癌；临床疗效
[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2015）11（b）-0127-02
[Abstract] Objective To observe the efficacy and safety of docetaxel combined with fluorouracil in the treatment of advanced gastric cancer. Methods A total of 168 patients with advanced gastric cancer admitted to this hospital from January 2012 to January 2015 were randomly divided into treatment group and control group with 84 in each one. The treatment group underwent chemotherapy using docetaxel combined with fluorouracil and the control group was treated with chemotherapy using docetaxel combined with S-1 for more than two courses with 3 weeks as one course. The improvement of people"s physical ability， short-term curative effect and adverse reactions to chemotherapy of the two groups were observed after treatment. Results No statistically significant difference can be found in the short-term effective rate of chemotherapy between the two groups， P>0.05. The improve...
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