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不同质子泵抑制剂联合莫沙必利治疗82例返流性食管炎的临床疗效观察

材料写作网    时间: 2020-06-13 04:38:00     阅读:

摘要:目的:研究莫沙必利与不同的质子泵抑制剂联合治疗返流性食管炎所产生的临床治疗效果。方法:选取我院2012年12月~2013年12月门诊以及住院部82例返流性食管炎患者为研究对象,将其按照治疗方式的不同分为观察组和对照组,观察组给予雷贝拉唑联合莫沙必利治疗,对照组给予奥美拉唑联合莫沙必利治疗,观察记录两组患者的疗效及不良反应情况,并进行分析比较。结果:观察组总有效率为95.12%,对照组总有效率为78.05%,两组患者总有效率比较χ2=5.0819(p=0.0242),差异具有统计学意义;总不良反应率比较χ2=0.7105(p=0.3993),差异无统计学意义。结论:雷贝拉唑联合莫沙必利对返流性食管炎的治疗效果显著,且不良反应发生率低,可作为临床治疗的首选方法。

关键词:返流性食管炎;莫沙必利;雷贝拉唑;奥美拉唑;临床疗效

Abstract: Objective: To observe the therapeutic effect of Mosapride combined with different proton pump inhibitors in treatment of reflux esophagitis generated. Methods: selected in our hospital in 2012 December ~2013 year in December the outpatient and inpatient department of 82 cases of reflux esophagitis patients as the research object, according to their different treatment methods for the observation group and the control group, the observation group was given ray Bella triazole mosapride treatment, control group was given Austria US pulls azole combined with Mosapride, observe and record the curative effect and adverse reaction of two groups of patients, and carries on the analysis comparison. Results: the total effective rate of observation group was 95.12%, the comparison group total effectiveness 78.05%, two groups of patients with total effective rate of X 2=5.0819 (p=0.0242), statistically significant differences; the total rate of adverse reactions compared x 2=0.7105 (p=0.3993), no significant difference. Conclusion: ray Bella triazole and Mosapride for reflux esophagitis significant treatment ...

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